Association of fasting glucose with lifetime risk of incident heart failure: the Lifetime Risk Pooling Project

Given the rising prevalence of dysglycemia and disparities in heart failure (HF) burden, we determined race- and sex-specific lifetime risk of HF across the spectrum of fasting plasma glucose (FPG). Individual-level data from adults without baseline HF was pooled from 6 population-based cohorts. Mod...

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Veröffentlicht in:Cardiovascular Diabetology 2021-03, Vol.20 (1), p.66-66, Article 66
Hauptverfasser: Sinha, Arjun, Ning, Hongyan, Ahmad, Faraz S, Bancks, Michael P, Carnethon, Mercedes R, O'Brien, Matthew J, Allen, Norrina B, Wilkins, John T, Lloyd-Jones, Donald M, Khan, Sadiya S
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Sprache:eng
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Zusammenfassung:Given the rising prevalence of dysglycemia and disparities in heart failure (HF) burden, we determined race- and sex-specific lifetime risk of HF across the spectrum of fasting plasma glucose (FPG). Individual-level data from adults without baseline HF was pooled from 6 population-based cohorts. Modified Kaplan-Meier analysis, Cox models adjusted for the competing risk of death, and Irwin's restricted mean were used to estimate the lifetime risk, adjusted hazard ratio (aHR), and years lived free from HF in middle-aged (40-59 years) and older (60-79 years) adults with FPG 
ISSN:1475-2840
1475-2840
DOI:10.1186/s12933-021-01265-y