Nasopharyngeal SARS-CoV-2 viral loads in young children do not differ significantly from those in older children and adults

The role of children in the spread of the SARS-CoV-2 coronavirus has become a matter of urgent debate as societies in the US and abroad consider how to safely reopen schools. Small studies have suggested higher viral loads in young children. Here we present a multicenter investigation on over five t...

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Veröffentlicht in:	Scientific reports 2021-02, Vol.11 (1), p.3044-3044, Article 3044
Hauptverfasser:	Madera, Sharline, Crawford, Emily, Langelier, Charles, Tran, Nam K., Thornborrow, Ed, Miller, Steve, DeRisi, Joseph L.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/326/596/2562 631/326/596/4130 Adolescent Adult Aged Aged, 80 and over California - epidemiology Child Child, Preschool Children Coronaviruses COVID-19 COVID-19 - diagnosis COVID-19 - virology COVID-19 Testing Female Humanities and Social Sciences Humans Male Middle Aged multidisciplinary Nasopharynx - virology Nucleic acids Reverse transcription RNA, Viral - analysis SARS-CoV-2 - genetics SARS-CoV-2 - physiology Schools Science Science (multidisciplinary) Severe acute respiratory syndrome coronavirus 2 Viral Load Young Adult
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Zusammenfassung:	The role of children in the spread of the SARS-CoV-2 coronavirus has become a matter of urgent debate as societies in the US and abroad consider how to safely reopen schools. Small studies have suggested higher viral loads in young children. Here we present a multicenter investigation on over five thousand SARS-CoV-2 cases confirmed by real-time reverse transcription (RT) PCR assay. Notably, we found no discernable difference in amount of viral nucleic acid among young children and adults.
ISSN:	2045-2322 2045-2322
DOI:	10.1038/s41598-021-81934-w