The Frailty of Advanced Kidney Disease: The Role of Mitochondria
Uremic toxins contribute to the impairment of mitochondrial function that subsequently could result in organ failure. Mitochondrial dysfunction also plays an essential role in the pathogenesis of sarcopenia in chronic kidney disease patients. It may be feasible to assess the effect of mitochondrial-...
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| Veröffentlicht in: | Turkish Journal of Nephrology 2022-07, Vol.31 (3), p.190-193 |
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| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
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| Online-Zugang: | Volltext |
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| Zusammenfassung: | Uremic toxins contribute to the impairment of mitochondrial function that subsequently could result in organ failure. Mitochondrial dysfunction also plays an essential role in the pathogenesis of sarcopenia in chronic kidney disease patients. It may be feasible to assess the effect of mitochondrial-targeted drugs to treat sarcopenia in patients with chronic kidney disease. Keywords: Chronic kidney disease, mitochondria, muscles |
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| ISSN: | 2667-4440 |
| DOI: | 10.5152/turkjnephrol.2022.22317 |