“Noninfective Endocarditis”: A Case Report of Hereditary Coagulation Disorders in a 28-Year-Old Male

We report a case of a young male who presented with acute limb ischemia after sport. With no prior history of disease, a non-infective endocarditis of the native aortic valve was diagnosed. After surgical valve replacement, the patient suffered from acute myocardial ischemia under phenprocoumon ther...

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Veröffentlicht in:Diagnostics (Basel) 2020-06, Vol.10 (6), p.384
Hauptverfasser: Reid, Gregory, Koechlin, Luca, Reuthebuch, Oliver, Rüter, Florian, Hopfer, Helmut, Eckstein, Friedrich, Santer, David
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Sprache:eng
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Zusammenfassung:We report a case of a young male who presented with acute limb ischemia after sport. With no prior history of disease, a non-infective endocarditis of the native aortic valve was diagnosed. After surgical valve replacement, the patient suffered from acute myocardial ischemia under phenprocoumon therapy. Anti-coagulant monitoring was subsequently changed to Factor II analysis after a rare Factor VII deficiency and prothrombin mutation (G20210A) was diagnosed.
ISSN:2075-4418
2075-4418
DOI:10.3390/diagnostics10060384