Evaluation of antibacterial, antioxidant, and anti-inflammatory properties of GC/MS characterized methanol leaf extract of Terminalia superba (Combretaceae, Engl. & Diels)

Background Terminalia superba is a well-known medicinal plant used in folk medicine for the management of various diseases and swelling. Validation of its efficacy in standardized scientific models is lacking. This gap needs to be filled as a way of enhancing modern drug discovery. The aim is to eva...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Future Journal of Pharmaceutical Sciences 2023-12, Vol.9 (1), p.3-15, Article 3
Hauptverfasser: Ani, Njideka Ifeoma, Okolo, Kenneth Obinna, Offiah, Raymond Ogbonna
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Background Terminalia superba is a well-known medicinal plant used in folk medicine for the management of various diseases and swelling. Validation of its efficacy in standardized scientific models is lacking. This gap needs to be filled as a way of enhancing modern drug discovery. The aim is to evaluate the antibacterial, antioxidant, and anti-inflammatory properties of T. superba in known and established models. Also, to establish and possibly correlate the established activity with the phytochemicals identified using GC/MS and qualitative methods. Results The result showed a dose-dependent percentage inhibition of DPPH, HO • , and Fe 3+ reducing activity. The antibacterial activity showed dose-dependent significant ( p  
ISSN:2314-7253
2314-7245
2314-7253
DOI:10.1186/s43094-022-00455-z