EFFECT OF INSULIN RESISTANCE ON CONNECTIVE TISSUE DYSPLASIA

The study included 111 patients (40 men and 71 women) with connective tissue dysplasia in conjunction with insulin resistance or without one. The mean age was 30,8±3,1 years. The study group (n=69) included patients with connective tissue dysplasia in conjunction with R & D. The control group (n=42) included patients with isolated connective tissue dysplasia. The aim of the study was to investigate the effect of insulin resistance on connective tissue dysplasia. All patients were evaluated vegetative status by collecting complaints according to the questionnaire Wayne A.M. and counting Kerdo index. We analyzed the frequency of cardiac arrhythmias and conduction according to the rest electrocardiography, the frequency and severity of dysplasia of heart by echocardiography. It has been established that insulin resistance significantly is a burden to vegetative dysfunction syndrome, increases the frequency of sinus tachycardia episodes, of the interval-QT prolongation, ventricular arrhythmia, increases the frequency and severity of mitral valve prolapse I degree.