Deep cutaneous ulcers and sinus formation in an immunocompetent adult

This report describes a case of unusual deep skin ulcers with tortuous sinus tract formation in an immunocompetent woman. She was initially diagnosed with a Staphylococcus aureus skin infection and histopathologically diagnosed with pyoderma gangrenosum. However, culture from the deep end of ribbon...

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Veröffentlicht in:Anais brasileiros de dermatología 2019-11, Vol.94 (6), p.744-746
Hauptverfasser: Zhou, Qiang, Zhu, Kejian
Format: Artikel
Sprache:eng
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Zusammenfassung:This report describes a case of unusual deep skin ulcers with tortuous sinus tract formation in an immunocompetent woman. She was initially diagnosed with a Staphylococcus aureus skin infection and histopathologically diagnosed with pyoderma gangrenosum. However, culture from the deep end of ribbon gauze inserted into the subcutaneous sinus tract revealed shiny, light-yellow mucoid colonies, which were identified as Cryptococcus neoformans var. grubii. She was treated with fluconazole for nine months and completely healed. Cryptococcosis is an opportunistic infection caused by variants of C. neoformans species. Cutaneous manifestations of cryptococcosis are quite divergent, rarely occurring as deep skin ulcers with sinus formation.
ISSN:0365-0596
1806-4841
1806-4841
DOI:10.1016/j.abd.2018.12.003