Higher premature atrial complex burden from the Holter examination predicts poor cardiovascular outcome

Premature atrial complexes (PACs) have been suggested to increase the risk of adverse events. The distribution of PAC burden and its dose–response effects on all-cause mortality and cardiovascular death had not been elucidated clearly. We analyzed 15,893 patients in a medical referral center from Ju...

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Veröffentlicht in:Scientific reports 2021-06, Vol.11 (1), p.12198-12198, Article 12198
Hauptverfasser: Huang, Ting-Chun, Lee, Po-Tseng, Huang, Mu-Shiang, Su, Pei-Fang, Liu, Ping-Yen
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Sprache:eng
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Zusammenfassung:Premature atrial complexes (PACs) have been suggested to increase the risk of adverse events. The distribution of PAC burden and its dose–response effects on all-cause mortality and cardiovascular death had not been elucidated clearly. We analyzed 15,893 patients in a medical referral center from July 1st, 2011, to December 31st, 2018. Multivariate regression driven by ln PAC (beats per 24 h plus 1) or quartiles of PAC burden were examined. Older group had higher PAC burden than younger group ( p for trend 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-021-91800-4