Synthesis and photophysical study of 2'-deoxyuridines labeled with fluorene derivatives

Synthesis and photophysical study of 2'-deoxyuridines labeled with fluorene derivatives

We examined microenvironment-sensitive fluorescent 2'-deoxyuridines labeled with fluorene derivatives that exhibited solvent-dependent photophysical properties. The high sensitivity of the fluorescence shift and the nucleoside intensity dependence on solvent polarity provided information useful...

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Veröffentlicht in:Molecules (Basel, Switzerland) Switzerland), 2012-10, Vol.17 (10), p.12061-12071
Hauptverfasser: Cho, Hyun Yi, Woo, Sang Keun, Hwang, Gil Tae
Format: Artikel
Sprache:eng
Schlagworte:
Deoxyuridine - chemical synthesis
Deoxyuridine - chemistry
dibenzofuran
dibenzothiophene
fluorene
Fluorenes - chemistry
fluorescence
Fluorescent Dyes - chemistry
nucleosides
Solvents
Spectrometry, Fluorescence
Staining and Labeling
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Zusammenfassung:We examined microenvironment-sensitive fluorescent 2'-deoxyuridines labeled with fluorene derivatives that exhibited solvent-dependent photophysical properties. The high sensitivity of the fluorescence shift and the nucleoside intensity dependence on solvent polarity provided information useful for estimating the polarity of the environment surrounding the fluorescent nucleoside.
ISSN:1420-3049
1420-3049
DOI:10.3390/molecules171012061