Effect of Antihypertensive Drugs on Placental Villi of Preeclamptic Patients: A Histopathological Study
Background & Aims: The placenta has been described as the most accurate record of the infant’s prenatal experience. The present study was a quantitative study and it was carried out to see the effect of pre-eclampsia on histopathology of placenta and the comparative changes in placenta of preec...
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Veröffentlicht in: | Journal of Research in Applied and Basic Medical Sciences 2022-05, Vol.8 (2), p.64-68 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Background & Aims: The placenta has been described as the most accurate record of the infant’s prenatal experience. The present study was a quantitative study and it was carried out to see the effect of pre-eclampsia on histopathology of placenta and the comparative changes in placenta of preeclamptic patients taking antihypertensives. Materials & Methods: A total of 60 patients were selected from the Obstetrics and Gynecology Department of Jawahar Lal Nehru Medical College & Hospital, AMU, Aligarh, UP, India and were grouped into control, untreated, and treated groups. Placenta of each group was fixed in 10% formalin solution and processed for section cutting. 5-micron thick sections were prepared and stained with Hematoxylin-eosin and Wiegerts & Van gieson stain and observed under the light of the microscope. A total of 200villi/hpf was counted and percentages for each parameter were expressed. Result: It has been shown that there was a significant reduction ( |
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ISSN: | 2717-0098 2717-0098 |
DOI: | 10.52547/rabms.8.2.64 |