Antibacterial and antibiotic-modifying activity of the commercialized essential oil of Copaifera spp. Associated with LED lights against a Staphylococcus aureus strain

[Display omitted] •The EOs of Copaifera spp. has a promising potential in modifying the antibiotic activity;•The combination with the red LED light potentiated the antibacterial activity of the EOs;•The red LED light potentiated the antibiotic activity against MDR bacteria; Copaiba oil is widely used in medicine due to its antibacterial, anti-inflammatory, healing, antiviral, antiseptic and analgesic properties. Thus, the main objective of the study is to evaluate the antibacterial activity and modifier of the antibiotic action of the commercialized essential oil of four species of Copaifera spp. in combination with Ampicillin and LED lights against the multidrug-resistant strain of S. aureus (SA 10). The essential oil was obtained commercially through the dōTERRA® company. The evaluation of the antibacterial and modulating activity was performed using the microdilution methodology in a 96-well plate, using blue 415 nm, red 620 nm and yellow 590 nm LEDs and Ampicillin at an initial concentration of 1.024 µg/mL. The experiments were carried out in triplicate and submitted to ANOVA statistical analysis, considering a significant value of p