The correlation between adiponectin with blood lipids and body mass index in women with type 2 diabetes

Background: Adiponectin, also called GBP-28, apM1, Adipo Q and Acrp30, is a novel adipose tissue-specific protein. A reduction in adiponectin expression is associated with insulin resistance in some animal models. This study was performed to determine the relationship between adiponectin with blood lipids and body mass index (BMI) in diabetic and healthy women. Methods: We examined serum levels of adiponectin, LDL-cholesterol, HDL-cholesterol, triglyceride and cholesterol in diabetic women (n=28) and healthy women (n=42). Adiponectin was measured by ELISA. We used Spearman coefficient to determine correlation between adiponectin with blood lipids and BMI in two studied groups. Results: We found that there was lower concentration of adiponectin in diabetic women (7.29±1.42 µg/ml) than healthy women (10.29 ± 1.93 µg/ml) (P