Methylation: a regulator of HIV-1 replication?

Recent characterizations of methyl transferases as regulators of cellular processes have spurred investigations into how methylation events might influence the HIV-1 life cycle. Emerging evidence suggests that protein-methylation can positively and negatively regulate HIV-1 replication. How DNA- and...

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Veröffentlicht in:	Retrovirology 2007-02, Vol.4 (1), p.9-9
Hauptverfasser:	Yedavalli, Venkat R K, Jeang, Kuan-Teh
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line DNA Methylation DNA, Viral - metabolism Gene Expression Regulation, Viral HIV-1 - genetics HIV-1 - metabolism HIV-1 - physiology Human immunodeficiency virus 1 Humans Methylation Methyltransferases - metabolism RNA, Viral - metabolism Viral Proteins - metabolism Virus Replication
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Zusammenfassung:	Recent characterizations of methyl transferases as regulators of cellular processes have spurred investigations into how methylation events might influence the HIV-1 life cycle. Emerging evidence suggests that protein-methylation can positively and negatively regulate HIV-1 replication. How DNA- and RNA- methylation might impact HIV-1 is also discussed.
ISSN:	1742-4690 1742-4690
DOI:	10.1186/1742-4690-4-9