P33-A110 Ex vivo models of corneal epithelial regeneration in bioreactor: respective roles of limbal, conjunctival and corneal epithelia

P33-A110 Ex vivo models of corneal epithelial regeneration in bioreactor: respective roles of limbal, conjunctival and corneal epithelia

PurposeHuman corneas preserved in bioreactor (BR) are characterized by not only a better endothelial viability, but also a more differentiated and stratified epithelium compared to corneas preserved in organoculture. By using corneal preservation in BR, we aimed to analyze the respective contributio...

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Veröffentlicht in:BMJ open ophthalmology 2023-08, Vol.8 (Suppl 2), p.A13-A14
Hauptverfasser: Coulomb, Louise, Perrache, Chantal, Guindolet, Damien, Poinard, Sylvain, est, Fabien, Gain, Philippe, He, Zhiguo, Thuret, Gilles
Format: Artikel
Sprache:eng
Schlagworte:
Cornea
Stem cells
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Zusammenfassung:PurposeHuman corneas preserved in bioreactor (BR) are characterized by not only a better endothelial viability, but also a more differentiated and stratified epithelium compared to corneas preserved in organoculture. By using corneal preservation in BR, we aimed to analyze the respective contribution of corneal (C), limbal (L), and conjunctival (Conj) epithelia in corneal epithelial regeneration.MethodsFive pairs of corneas from body donation to Science were used with a death-to-collection time
ISSN:2397-3269
2397-3269
DOI:10.1136/bmjophth-2023-EEBA.32