A Randomized Control Study on the Efficacy of Thymectomy in Patients with Nonthymomatous (without Chest Tumor) Myasthenia Gravis

To quantitatively compare the severity of symptoms for group SM and group M patients at diagnosis and 3, 6, 9, 12, and 15 months after diagnosis, Quautitative myasthenia score (QMGScore) publishedby Myasthenia Gravis Foundation of America (MGFA), manual muscle testing (MMT)-Cranial nerves score, MMT-organism score, total MMT score, and activities of daily living (ADL) score tests score were used. [...]for repeated measurement data analysis, random effect model (or panel regression model) was used to analyze the interaction of time-grouping factors, and the results showed that there was no statistical difference in the slope between the two groups (P = 0.160). For repeated measurement data analysis, it showed that the residual was skewed and significant difference was identified in slope between the two groups (P = 0.009), suggesting that the changes in total MMT score of group SM were higher than that in group M.[INLINE:5] In standardized ADL score [Table S6], no difference was showed for group M and group SM patients at diagnosis. [INLINE:8] In a report given by the Quality Standards Subcommittee of the American Academy of Neurology, the following characteristics from controlled studies were abstracted: method and setting of cohort assembly, years during which patients were enrolled in the cohort, number of subjects assembled, duration of follow-up, proportion of subjects lost to follow-up, and the thymectomy techniques used.