Treatment of hyponatremia in children with acute bacterial meningitis

PurposeFew studies have evaluated hyponatremia management in children with bacterial meningitis (BM). Thus, we aimed to describe variations in clinical practice, the effectiveness of sodium management, and adverse outcomes in children with BM and hyponatremia. MethodsThis retrospective cross-section...

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Veröffentlicht in:Frontiers in neurology 2022-08, Vol.13, p.911784-911784
Hauptverfasser: Zheng, Feixia, Ye, Xiaoyan, Chen, Yuanyuan, Wang, Hongying, Fang, Shiyu, Shi, Xulai, Lin, Zhongdong, Lin, Zhenlang
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Sprache:eng
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Zusammenfassung:PurposeFew studies have evaluated hyponatremia management in children with bacterial meningitis (BM). Thus, we aimed to describe variations in clinical practice, the effectiveness of sodium management, and adverse outcomes in children with BM and hyponatremia. MethodsThis retrospective cross-sectional study conducted at a tertiary institution analyzed participants' demographic, clinical, and sodium-altering treatment data. The sodium trigger for treatment was defined as pretreatment sodium level, with response and overcorrection defined as increments of ≥5 and >10 mmol/L after 24 h, respectively. ResultsThis study enrolled 364 children with BM (age:
ISSN:1664-2295
1664-2295
DOI:10.3389/fneur.2022.911784