Study the Efficacy of Antimicrobial Activities of Eight Clinically Applied Disinfectants against Clinical Isolated of Enterococci and Pseudomonas aeruginosa

Article Info Article History: Received: 22 July 2016 Accepted: 14 December 2016 ePublished: 30 June 2017 Keywords: -Hospital disinfectants - Enterococci -Pseudomonas aeruginosa -Clinical isolates -Antibiogram ABSTRACT Background: Hospital-acquired infections are among the most significant reasons of human mortality world-wide which can be controlled by efficient application of suitable disinfectant for hospital setting. Bacterial spores, mycobacteria and Gram-negative bacteria are insusceptible to biocides due to the presence of impermeable cell layers. Gram-positive bacteria, especially cocci are the most vulnerable types of microbes to biocides.1,2 Enterococcus spp. which are resistant to antimicrobial agents play an important role as nosocomial pathogens in hospital outbreaks.3 As US nosocomial infections claimed, enterococcal disease ranked in among 3 or 4 most prevalent hospital-acquired disease. Enterococcal urinary tract infections (UTIs), bacteremia and uncomplicated wound infections are the most common and meningitis as well as endocarditis is less frequent infections caused by these microorganisms.4,5 P. aeruginosa has emerged as an important cause of nosocomial infections among hospitalized patients, including pneumonia (hospital-acquired, healthcare-associated and ventilator-associated), burn infections, UTIs, meningitis and bacteremia. [...]selection of suitable antimicrobial agents is essential in health-care centers.4'6,7 In hospitals and health care facilities, biocides are widely used to prevent and control hospital-acquired infections. [...]there is a growing concern regard to maintaining the sanitary condition in hospitals. Because of the emergence of resistant bacteria to different antibiotics and silver compounds as well as widespread usage of disinfectants in hospitals, more researches are necessary to evaluate the efficacy of active biocidal substances not only on standard...