A PIK3CA-mutant breast cancer metastatic patient-derived organoid approach to evaluate alpelisib treatment for multiple secondary lesions

Keywords: Breast cancer metastases, Organoids, Alpelisib, PIK3CA mutations

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Bibliographische Detailangaben
Veröffentlicht in:	Molecular cancer 2022-07, Vol.21 (1), p.152-152, Article 152
Hauptverfasser:	Donzelli, Sara, Cioce, Mario, Sacconi, Andrea, Zanconato, Francesca, Daralioti, Theodora, Goeman, Frauke, Orlandi, Giulia, Di Martino, Simona, Fazio, Vito Michele, Alessandrini, Gabriele, Telera, Stefano, Carosi, Mariantonia, Ciliberto, Gennaro, Botti, Claudio, Strano, Sabrina, Piccolo, Stefano, Blandino, Giovanni
Format:	Artikel
Sprache:	eng
Schlagworte:	Alpelisib Breast cancer Breast cancer metastases Breast Neoplasms - drug therapy Breast Neoplasms - genetics Breast Neoplasms - pathology Cancer patients Cancer therapies Care and treatment Class I Phosphatidylinositol 3-Kinases - genetics Correspondence ErbB-2 protein Female Flow cytometry Genes Humans Invasiveness Lung cancer Lung nodules Medical research Medicine, Experimental Metastases Metastasis Mutation Organoids Organoids - pathology Patients PIK3CA mutations Thiazoles Tomography Tumors
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Beschreibung
Zusammenfassung:	Keywords: Breast cancer metastases, Organoids, Alpelisib, PIK3CA mutations
ISSN:	1476-4598 1476-4598
DOI:	10.1186/s12943-022-01617-6