Synthesis, Characterization and Biological Activities of 3,5‐Diaryltetrahydro‐N‐[(phenylamino)methyl]‐1,4‐thiazine‐1,1‐dioxide

Synthesis of 3,5‐diaryltetrahydro‐N‐ [(4’‐nitroanilino)methyl‐thiazine‐1,1‐dioxide and N ‐[(4’‐methylanilino)methyl‐]‐1,4‐thiazine‐1,1‐dioxides by condensing 3,5‐diaryl‐tetrahydro‐1,4‐thiazine‐1,1‐dioxide with formaldehyde and 4‐nitroaniline/4‐methylaniline in the presence of hydrochloric acid is re...

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Veröffentlicht in:E-journal of chemistry 2009-01, Vol.6 (1), p.177-182
Hauptverfasser: Sundari, V., Nagarajan, G., Gurumurthy, S., Valliappan, R.
Format: Artikel
Sprache:eng
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Zusammenfassung:Synthesis of 3,5‐diaryltetrahydro‐N‐ [(4’‐nitroanilino)methyl‐thiazine‐1,1‐dioxide and N ‐[(4’‐methylanilino)methyl‐]‐1,4‐thiazine‐1,1‐dioxides by condensing 3,5‐diaryl‐tetrahydro‐1,4‐thiazine‐1,1‐dioxide with formaldehyde and 4‐nitroaniline/4‐methylaniline in the presence of hydrochloric acid is reported. The structures of the synthesized compounds have been confirmed by elemental and spectral analysis. The preliminary screening of the compounds for their biological activities gives significant results
ISSN:2090-9063
0973-4945
2090-9071
2090-9810
DOI:10.1155/2009/254747