Synthesis, Characterization and Biological Activities of 3,5‐Diaryltetrahydro‐N‐[(phenylamino)methyl]‐1,4‐thiazine‐1,1‐dioxide
Synthesis of 3,5‐diaryltetrahydro‐N‐ [(4’‐nitroanilino)methyl‐thiazine‐1,1‐dioxide and N ‐[(4’‐methylanilino)methyl‐]‐1,4‐thiazine‐1,1‐dioxides by condensing 3,5‐diaryl‐tetrahydro‐1,4‐thiazine‐1,1‐dioxide with formaldehyde and 4‐nitroaniline/4‐methylaniline in the presence of hydrochloric acid is re...
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Veröffentlicht in: | E-journal of chemistry 2009-01, Vol.6 (1), p.177-182 |
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Hauptverfasser: | , , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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Zusammenfassung: | Synthesis of 3,5‐diaryltetrahydro‐N‐ [(4’‐nitroanilino)methyl‐thiazine‐1,1‐dioxide and N ‐[(4’‐methylanilino)methyl‐]‐1,4‐thiazine‐1,1‐dioxides by condensing 3,5‐diaryl‐tetrahydro‐1,4‐thiazine‐1,1‐dioxide with formaldehyde and 4‐nitroaniline/4‐methylaniline in the presence of hydrochloric acid is reported. The structures of the synthesized compounds have been confirmed by elemental and spectral analysis. The preliminary screening of the compounds for their biological activities gives significant results |
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ISSN: | 2090-9063 0973-4945 2090-9071 2090-9810 |
DOI: | 10.1155/2009/254747 |