他汀在缺血性卒中一级预防中的作用 The Role of Statin in Primary Prevention of Ischemic Stroke

他汀类药物是降脂药物中安全性和耐受性较好的药物，在动脉粥样硬化性心脑血管疾病 患者中已经普及使用。许多研究显示缺血性卒中发病前使用他汀药物可以降低卒中发病风险、减轻卒 中发病严重程度以及改善患者预后等。本文将对他汀在缺血性卒中一级预防中的作用进行综述，为 临床上规范使用他汀类药物提供参考。 Abstract: Statin is one of safe and well-tolerant prescriptions in lipid-lowering drugs, and widely used in patients with atherosclerotic cardiovascular and cerebrovascular diseases. Many studies have identified the effective role of statin in reducing the incidence and severity of stroke and improving functional outcomes in stroke patients. This article is aim to review the evidence of statin for the primary prevention of ischemic stroke, providing reference for standard clinical practice.