Exertional intolerance and dyspnea with preserved lung function: an emerging long COVID phenotype?
The COVID-19 pandemic has resulted in significant acute morbidity and mortality worldwide. There is now a growing recognition of the longer-term sequelae of this infection, termed “long COVID”. However, little is known about this condition. Here, we describe a distinct phenotype seen in a subset of...
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Veröffentlicht in: | Respiratory research 2021-08, Vol.22 (1), p.1-222, Article 222 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | The COVID-19 pandemic has resulted in significant acute morbidity and mortality worldwide. There is now a growing recognition of the longer-term sequelae of this infection, termed “long COVID”. However, little is known about this condition. Here, we describe a distinct phenotype seen in a subset of patients with long COVID who have reduced exercise tolerance as measured by the 6 min walk test. They are associated with significant exertional dyspnea, reduced health-related quality of life and poor functional status. However, surprisingly, they do not appear to have any major pulmonary function abnormalities or increased burden of neurologic, musculoskeletal or fatigue symptoms. |
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ISSN: | 1465-993X 1465-9921 1465-993X 1465-9921 |
DOI: | 10.1186/s12931-021-01814-9 |