Ocrelizumab-Induced Severe Colitis

Ocrelizumab-Induced Severe Colitis

We report a case of severe ocrelizumab (anti-CD20 monoclonal antibody) induced colitis in a 43-year-old woman with multiple sclerosis leading to total colectomy after failing medical therapy. Histology of the colectomy was consistent with medication-induced colitis.

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Veröffentlicht in:Case reports in gastrointestinal medicine 2020, Vol.2020 (2020), p.1-4
Hauptverfasser: Strey, Gabriela, Bermingham, Daniel, Sritharan, Naveen, Lee, Hsing Hwa
Format: Artikel
Sprache:eng
Schlagworte:
Abdomen
Antigens
Case Report
Case reports
Colon
Cytomegalovirus
Histology
Immune system
Infections
Inflammatory bowel disease
Laboratories
Monoclonal antibodies
Multiple sclerosis
Ostomy
Patients
Rodents
X-rays
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Zusammenfassung:We report a case of severe ocrelizumab (anti-CD20 monoclonal antibody) induced colitis in a 43-year-old woman with multiple sclerosis leading to total colectomy after failing medical therapy. Histology of the colectomy was consistent with medication-induced colitis.
ISSN:2090-6528
2090-6536
DOI:10.1155/2020/8858378