Factors Associated with Thrombosis in Primary Immune Thrombocytopenia

BackgroundPatients with primary immune thrombocytopenia (ITP) , a hemorrhagic disease characterized by thrombocytopenia, have increased incidence of thrombotic events, which increases the treatment difficulty. Therefore, it is necessary to determine the risk factors for thrombosis in ITP.ObjectiveTo identify the factors associated with thrombosis in ITP.MethodsSeven hundred and twenty-five ITP inpatients (including individuals with and without thrombosis) were recruited from the First People's Hospital of Shangqiu. Demographics and results of testing for antiphospholipid antibodies and thrombosis type were collected retrospectively. Multivariate Logistic regression analysis was used to explore the influencing factors of thrombosis.ResultsPatients with thrombosis (n=704, 97.1%) had higher rates of 50-year-olds and above, having hypertension history, diabetes history, and splenectomy, and higher prevalence of use of hormone over 8 weeks, lupus anticoagulant positivity, as well as anticardiolipin antibody positi