Rare Tumors: Opportunities and challenges from the Children’s Oncology Group perspective
While all childhood cancers are rare, tumors that are particularly infrequent or underrepresented within pediatrics are studied under the umbrella of the Children’s Oncology Group Rare Tumor committee, divided into the Retinoblastoma and Infrequent Tumor subcommittees. The Infrequent Tumor subcommit...
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Veröffentlicht in: | EJC paediatric oncology 2023-12, Vol.2, p.100024, Article 100024 |
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Sprache: | eng |
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Zusammenfassung: | While all childhood cancers are rare, tumors that are particularly infrequent or underrepresented within pediatrics are studied under the umbrella of the Children’s Oncology Group Rare Tumor committee, divided into the Retinoblastoma and Infrequent Tumor subcommittees. The Infrequent Tumor subcommittee has traditionally included an emphasis on globally rare tumors such as adrenocortical carcinoma, nasopharyngeal carcinoma, or those tumors that are rare in young children, despite being common in adolescents and young adults, such as colorectal carcinoma, thyroid carcinoma, and melanoma. Pleuropulmonary blastoma, gonadal stromal tumors, pancreatic tumors including pancreatoblastoma, gastrointestinal stromal tumor, nonmelanoma skin cancers, neuroendocrine tumors, and desmoplastic small round cell tumors, as well as other carcinomas are also included under the heading of the Children’s Oncology Group Rare Tumor committee. While substantial challenges exist in rare cancers, inclusion and global collaboration remain key priorities to ensure high quality research to advance care.
•Children’s Oncology Group (COG) includes more 200 institutions worldwide.•COG’s Rare Tumor committee encompasses Retinoblastoma and Infrequent Tumors.•Efforts focus on prospective clinical trials and elucidation of tumor biology.•International collaboration remains a key priority to advance rare cancer research. |
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ISSN: | 2772-610X 2772-610X |
DOI: | 10.1016/j.ejcped.2023.100024 |