A case report on atypical presentations of Dyke-Davidoff-Masson syndrome

Dyke-Davidoff-Masson Syndrome (DDMS) is a rare neurological disease with an unknown incidence. The manifestations of DDMS are variable, while typical symptoms are seizures, hemiparesis, and mental retardation. Here, we present a case involving a 19-year-old male patient who presents with headaches, mood changes, and a history of seizures during childhood. Based on the neuroimages, a diagnosis of DDMS was established. The application of sertraline hydrochloride as a therapeutic intervention has alleviated the symptoms. This case report illustrates the importance of understanding the clinical features of DDMS based on imaging. •Dyke-Davidoff-Masson Syndrome (DDMS) is a rare neurological disease.•The clinical presentation we report in this case of DDMS is atypical.•Through this case, the diagnosis and treatment of the DDMS can be further promoted.