Effects of an untreated medial meniscal ramp lesion on histological deterioration findings of the medial meniscus: A study in a porcine anterior cruciate ligament reconstruction model
Purpose To evaluate the effect of untreated medial meniscal ramp lesions (MMRLs) on the tendon graft after anterior cruciate ligament (ACL) reconstruction and histological findings of medial meniscus (MM) in a porcine a model. Methods A total of 17 pigs were divided into two groups: (1) the untreate...
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Veröffentlicht in: | Journal of experimental orthopaedics 2024-07, Vol.11 (3), p.e70027-n/a |
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Sprache: | eng |
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Zusammenfassung: | Purpose
To evaluate the effect of untreated medial meniscal ramp lesions (MMRLs) on the tendon graft after anterior cruciate ligament (ACL) reconstruction and histological findings of medial meniscus (MM) in a porcine a model.
Methods
A total of 17 pigs were divided into two groups: (1) the untreated MMRL group (UM group, n = 9) and (2) intact MM group (n = 8) and euthanized 12 weeks after surgery. The specimens were then tested cyclically and loaded to failure. Side‐to‐side differences (SSDs) in translation under cyclic loading and structural properties were analyzed. Histological evaluation of the MM was also performed.
Results
No significant differences in the SSD in translation during the cyclic testing (UM group, 0.3 ± 0.4 mm; intact MM group, 0.1 ± 1.4 mm), upper yield load (UM group, 476.3 ± 399.9 N; intact MM group, 643.2 ± 302.9 N), maximum load (UM group, 539.5 ± 265.8 N; intact MM group, 705.8 ± 282.6 N), linear stiffness (UM group, 63.5 ± 39.0 N/mm; intact MM group, 73.7 ± 60.1 N/mm) and elongation at failure (UM group, −4.6 ± 16.3 mm; intact MM group, 2.3 ± 6.6 mm) were observed. However, the UM group had significantly worse Modified Mankin's histological grading scores (1.8 ± 0.4 [1–2] vs. 0 ± 0 [0]; p |
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ISSN: | 2197-1153 2197-1153 |
DOI: | 10.1002/jeo2.70027 |