Structure of a type IV secretion system core complex encoded by multi-drug resistance F plasmids

Bacterial type IV secretion systems (T4SSs) are largely responsible for the proliferation of multi-drug resistance. We solved the structure of the outer-membrane core complex (OMCC F ) of a T4SS encoded by a conjugative F plasmid at

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Bibliographische Detailangaben
Veröffentlicht in:	Nature communications 2022-01, Vol.13 (1), p.379-379, Article 379
Hauptverfasser:	Liu, Xiangan, Khara, Pratick, Baker, Matthew L., Christie, Peter J., Hu, Bo
Format:	Artikel
Sprache:	eng
Schlagworte:	101/28 38/22 38/77 42/44 42/70 631/326/41/2180 631/326/41/2536 631/535/1258/1259 82/1 82/16 82/29 82/58 82/80 82/83 Cell Membrane - chemistry Deoxyribonucleic acid DNA Domains Drug resistance Drug Resistance, Multiple, Bacterial Escherichia coli - metabolism Escherichia coli Proteins - chemistry Escherichia coli Proteins - metabolism F Factor - metabolism Humanities and Social Sciences Membranes Models, Molecular multidisciplinary Multidrug resistance Plasmids Science Science (multidisciplinary) Secretion Symmetry Type IV Secretion Systems - chemistry Type IV Secretion Systems - ultrastructure
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Beschreibung
Zusammenfassung:	Bacterial type IV secretion systems (T4SSs) are largely responsible for the proliferation of multi-drug resistance. We solved the structure of the outer-membrane core complex (OMCC F ) of a T4SS encoded by a conjugative F plasmid at
ISSN:	2041-1723 2041-1723
DOI:	10.1038/s41467-022-28058-5