A case of pulmonary transthyretin amyloidosis with concurrent mycobacterial tuberculosis infection

Amyloidosis is a pathological deposition disease that causes a spectrum of organ dysfunction. Pulmonary involvement is generally associated with immunoglobulin light chain type (AL) amyloid. Transthyretin (ATTR) amyloid build up in the lung is thought to be a senile disease observed usually as a finding at autopsy. We describe a case of pulmonary ATTR amyloidosis with concurrent mycobacterial tuberculosis infection. Amyloidosis is a pathological deposition disease that causes a spectrum of organ dysfunction. Lung involvement of transthyretin (ATTR) amyloid is thought to be a senile disease observed usually as a finding at autopsy. We describe the first case of pulmonary ATTR amyloidosis from Australia with concurrent mycobacterial tuberculosis infection.