EFFICACY OF COMBINED NICLOSAMIDE-BASED DRUG AGAINST ANOPLOCEPHALA SPP. OF DIFFERENT TYPES AND AGES

Effect of Vigisox, Praziquantel, Fenbendazole, Albendazole and Niclozamide at the doses of 60, 3, 10, 10 and 100 mg/kg respectively applied against Moniezia spp. of different ages in sheep spontaneously infected with Moniezia expansa and M. benedeni is studied. Efficacy of drugs applied against mature Moniezia spp., was the following: Vigisox, Niclozamide and Praziquantel – 100 %, Albendazole – 88, Fenbendazole – 84 %, and against immature Moniezia spp.: Vigisox, Niclozamide – 89,3 %, Praziquantel – 100, Albendazole – 75 and Fenbendazole – 64,3 % respectively. The results shown a non significant difference in efficacy of Vigisox applied against various types of Anoplocephala spp. The drug at a dose of 60 mg/kg has shown a 97,9 % efficacy against M. expansa, 97,5 % – M. benedeni, 98,9 % – Thysaniezia giardi. While conducting preimaginal dehelminthizations of animals it is necessary to apply anthelmintics taking into account their effect on immature Moniezia spp.