A Double-Blind, Placebo Controlled, Randomized Trial to Assess the Impact of a Monthly Administration of 50,000 IU of Vitamin D3 for 6 Months on Serum Levels of 25-Hydroxyvitamin D in Healthy Young Adults

In this double blind, unicentre, randomized, placebo controlled study, we evaluated the changes in 25-hydroxyvitamin D (25(OH)D) serum levels in 150 young Belgian adults (18–30 years), monthly supplemented with 50,000 IU of vitamin D (VTD) or placebo for 6 months, from November 2010 to May 2011. At...

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Veröffentlicht in:	International Journal of Endocrinology 2013-01, Vol.2013 (2013), p.318-323-136
Hauptverfasser:	Brunel, E., Schnitzler, M., Foidart-Dessalle, M., Souberbielle, J. C., Cavalier, E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alfacalcidol Analysis Calcifediol Clinical Study Dietary supplements Double-blind studies Drug dosages Endocrinology Health aspects Human health sciences Laboratories Laboratory medicine & medical technology Measurement Médecine de laboratoire & technologie médicale Older people Osteoporosis Population Sciences de la santé humaine Statistical analysis Variance analysis Vitamin D Vitamin deficiency
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Beschreibung
Zusammenfassung:	In this double blind, unicentre, randomized, placebo controlled study, we evaluated the changes in 25-hydroxyvitamin D (25(OH)D) serum levels in 150 young Belgian adults (18–30 years), monthly supplemented with 50,000 IU of vitamin D (VTD) or placebo for 6 months, from November 2010 to May 2011. At T0, 30% of the population presented 25(OH)D serum levels below 20 ng/mL. In the VTD-treated group, mean serum levels increased from 21.2 ± 8.2 to 30.6 ± 8.8 ng/mL (P
ISSN:	1687-8337 1687-8345 1687-8345
DOI:	10.1155/2013/652648