ECMO is associated with decreased hospital mortality in COVID-19 ARDS

This study determined whether compared to conventional mechanical ventilation (MV), extracorporeal membrane oxygenation (ECMO) is associated with decreased hospital mortality or fibrotic changes in patients with COVID-19 acute respiratory distress syndrome. A cohort of 72 patients treated with ECMO...

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Veröffentlicht in:	Scientific reports 2024-06, Vol.14 (1), p.14835-10, Article 14835
Hauptverfasser:	Kim, Won-Young, Jung, Sun-Young, Kim, Jeong-Yeon, Chae, Ganghee, Kim, Junghyun, Joh, Joon-Sung, Park, Tae Yun, Baek, Ae-Rin, Jegal, Yangjin, Chung, Chi Ryang, Lee, Jinwoo, Cho, Young-Jae, Park, Joo Hun, Hwang, Jung Hwa, Song, Jin Woo
Format:	Artikel
Sprache:	eng
Schlagworte:	692/499 692/700/1750 Adult Aged Comorbidity COVID-19 COVID-19 - complications COVID-19 - mortality COVID-19 - therapy Extracorporeal membrane oxygenation Extracorporeal Membrane Oxygenation - methods Female Hospital Mortality Humanities and Social Sciences Humans Male Mechanical ventilation Middle Aged Mortality multidisciplinary Oxygenation Patients Respiration, Artificial Respiratory distress syndrome Respiratory Distress Syndrome - mortality Respiratory Distress Syndrome - therapy Respiratory Distress Syndrome - virology SARS-CoV-2 - isolation & purification Science Science (multidisciplinary)
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Zusammenfassung:	This study determined whether compared to conventional mechanical ventilation (MV), extracorporeal membrane oxygenation (ECMO) is associated with decreased hospital mortality or fibrotic changes in patients with COVID-19 acute respiratory distress syndrome. A cohort of 72 patients treated with ECMO and 390 with conventional MV were analyzed (February 2020–December 2021). A target trial was emulated comparing the treatment strategies of initiating ECMO vs no ECMO within 7 days of MV in patients with a PaO 2 /FiO 2
ISSN:	2045-2322 2045-2322
DOI:	10.1038/s41598-024-64949-x