Severe Hemolysis in a COVID-19 Patient with Paroxysmal Nocturnal Hemoglobinuria
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (COVID-19), has been demonstrated to be able to activate complement, making patients with deficiency in negative complement regulation, such as paroxysmal nocturnal hemoglobinuria (PNH), part...
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Veröffentlicht in: | Case reports in hematology 2021-07, Vol.2021, p.1-6 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (COVID-19), has been demonstrated to be able to activate complement, making patients with deficiency in negative complement regulation, such as paroxysmal nocturnal hemoglobinuria (PNH), particularly vulnerable to complement-mediated cell damage. We report a case of a patient who presented with fatigue, facial swelling, and upper respiratory infection (URI) symptoms and was found to have COVID-19 with laboratory tests showing severe hemolysis and pancytopenia secondary to PNH. |
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ISSN: | 2090-6560 2090-6579 |
DOI: | 10.1155/2021/6619177 |