Human adenovirus among hospitalized children with respiratory tract infections in Beijing, China, 2017-2018

Human adenoviruses (HAdVs) cause a wide range of diseases. However, the genotype diversity and epidemiological information relating to HAdVs among hospitalized children with respiratory tract infections (RTIs) is limited. Here, we describe the epidemiology and genotype distribution of HAdVs associat...

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Veröffentlicht in:	Virology journal 2019-06, Vol.16 (1), p.78-78, Article 78
Hauptverfasser:	Yao, Li-Hong, Wang, Chao, Wei, Tian-Li, Wang, Hao, Ma, Fen-Lian, Zheng, Li-Shu
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenovirus Infections, Human - epidemiology Adenovirus Infections, Human - virology Adenoviruses Adenoviruses, Human - genetics Adenoviruses, Human - isolation & purification Adolescent Backup software Beijing - epidemiology Child Child, Preschool Children China Complications and side effects computer software Cough data analysis Deoxyribonucleic acid Diagnosis Disease DNA Enterovirus Epidemiology FDA approval Female Fever Gene expression Genes Genetic aspects Genetic Variation Genotype Genotypes Hospital patients Hospitalization Hospitalization - statistics & numerical data Hospitals Human adenovirus Human adenoviruses Humans Infant Infant, Newborn Infections Influenza Male Mastadenovirus mixed infection Nasopharynx - virology Parainfluenza patients Pediatrics Phylogenetics Phylogeny Pneumonia Polymerase chain reaction Prevalence quantitative polymerase chain reaction Radiography Real-Time Polymerase Chain Reaction Respiratory diseases Respiratory tract diseases Respiratory tract infection Respiratory tract infections Respiratory Tract Infections - epidemiology Respiratory Tract Infections - virology Rhinovirus Risk factors Sequence Analysis, DNA Software summer Viral Load Viral proteins Viruses
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Zusammenfassung:	Human adenoviruses (HAdVs) cause a wide range of diseases. However, the genotype diversity and epidemiological information relating to HAdVs among hospitalized children with respiratory tract infections (RTIs) is limited. Here, we describe the epidemiology and genotype distribution of HAdVs associated with RTIs in Beijing, China. Nasopharyngeal aspirates (NPA) were collected from hospitalized children with RTIs from April 2017 to March 2018. HAdVs were detected by a TaqMan-based quantitative real-time polymerase chain reaction (qPCR) assay, and the hexon gene was used for phylogenetic analysis. Epidemiological data were analyzed using statistical product and service solutions (SPSS) 21.0 software. HAdV was detected in 72 (5.64%) of the 1276 NPA specimens, with most (86.11%, 62/72) HAdV-positives cases detected among children
ISSN:	1743-422X 1743-422X
DOI:	10.1186/s12985-019-1185-x