Determinants of bone health in elderly Japanese men: study design and key findings of the Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) cohort study

The Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) study was launched to investigate risk factors for osteoporotic fractures, interactions of osteoporosis with other non-communicable chronic diseases, and effects of fracture on QOL and mortality. FORMEN baseline study participants (in 2007 and 2008)...

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Veröffentlicht in:Environmental health and preventive medicine 2021-04, Vol.26 (1), p.51-51, Article 51
Hauptverfasser: Fujita, Yuki, Tamaki, Junko, Kouda, Katsuyasu, Yura, Akiko, Sato, Yuho, Tachiki, Takahiro, Hamada, Masami, Kajita, Etsuko, Kamiya, Kuniyasu, Kaji, Kazuki, Tsuda, Koji, Ohara, Kumiko, Moon, Jong-Seong, Kitagawa, Jun, Iki, Masayuki
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Sprache:eng
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Zusammenfassung:The Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) study was launched to investigate risk factors for osteoporotic fractures, interactions of osteoporosis with other non-communicable chronic diseases, and effects of fracture on QOL and mortality. FORMEN baseline study participants (in 2007 and 2008) included 2012 community-dwelling men (aged 65-93 years) in Nara prefecture, Japan. Clinical follow-up surveys were conducted 5 and 10 years after the baseline survey, and 1539 and 906 men completed them, respectively. Supplemental mail, telephone, and visit surveys were conducted with non-participants to obtain outcome information. Survival and fracture outcomes were determined for 2006 men, with 566 deaths identified and 1233 men remaining in the cohort at 10-year follow-up. The baseline survey covered a wide range of bone health-related indices including bone mineral density, trabecular microarchitecture assessment, vertebral imaging for detecting vertebral fractures, and biochemical markers of bone turnover, as well as comprehensive geriatric assessment items. Follow-up surveys were conducted to obtain outcomes including osteoporotic fracture, cardiovascular diseases, initiation of long-term care, and mortality. A complete list of publications relating to the FORMEN study can be found at https://www.med.kindai.ac.jp/pubheal/FORMEN/Publications.html .
ISSN:1342-078X
1347-4715
DOI:10.1186/s12199-021-00972-y