Prognostic factors of palatal adenoid cystic carcinoma: A single‐center analysis of 85 cases

Objective The purpose of this retrospective study was to describe the clinicopathological characteristics of primary adenoid cystic carcinoma (ACC) of the palate and to identify the factors affecting prognosis. Methods The medical records of 85 patients with primary ACC of the palate treated with su...

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Veröffentlicht in:Laryngoscope Investigative Otolaryngology 2024-04, Vol.9 (2), p.e1236-n/a
Hauptverfasser: Gu, Baoxin, Chi, Yanting, Wu, Wenjie, Zhong, Yiwei, Zhang, Jianyun, Zhang, Jie
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Sprache:eng
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Zusammenfassung:Objective The purpose of this retrospective study was to describe the clinicopathological characteristics of primary adenoid cystic carcinoma (ACC) of the palate and to identify the factors affecting prognosis. Methods The medical records of 85 patients with primary ACC of the palate treated with surgery, with or without adjuvant radiotherapy/chemotherapy, from 2009 to 2019 were reviewed. The relationship of different clinical parameters with locoregional recurrence (LR), distant metastasis (DM), and overall survival (OS) were analyzed. Results Median follow‐up time was 44.6 months. LR and DM rates were 24.7% and 25.9%, respectively, and the 5‐year OS and disease‐free survival (DFS) rates were 85.9% and 55.1%, respectively. Multivariate analysis showed that positive margins were independently associated with the risk of LR (p 
ISSN:2378-8038
2378-8038
DOI:10.1002/lio2.1236