Effects of Ganoderma lingzhi Polysaccharides Combined with Aerobic Exercise on Lipid-lowering and Antioxidant Levels in Hyperlipidemia Mice

To explore the effects of Ganoderma lingzhi fruiting body polysaccharide combined with aerobic exercise on the lipid-lowering and antioxidant levels of high-fat mice. The crude polysaccharide of Ganoderma lingzhi fruit body was extracted by water extraction and alcohol precipitation, and then purified by deproteinization, separation and purification to obtain pure Ganoderma lingzhi polysaccharide (GLP). The structural characteristics of GLP were analyzed by scanning electron microscope and Fourier infrared spectroscopy. A high-fat mouse model was constructed by feeding high-fat diets, including normal feeding group (CG), high-fat diet group (HD), Ganoderma lingzhi polysaccharide group (GLP), Aerobic exercise control group (AE) and Ganoderma lingzhi polysaccharide and aerobic exercise combined group (GLP/AE), GLP group and GLP/AE group were given Ganoderma lingzhi polysaccharide gavage at a dose of 2.0 g/kg/d, and the rest groups were given the same amount of normal saline, and the AE group and GLP/AE group we