Treatment patterns and achievement of the treat-to-target goals in a real-life rheumatoid arthritis patient cohort: data from 1317 patients

Treatment patterns and achievement of the treat-to-target goals in a real-life rheumatoid arthritis patient cohort: data from 1317 patients

Background: Data regarding the real-life predictors of low disease activity (LDA) in rheumatoid arthritis (RA) patients are limited. Our aim was to evaluate the rate and predictors of LDA and treatment patterns in RA. Methods: This was a multicenter, prospective, RA cohort study where patients were...

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Veröffentlicht in:Therapeutic advances in musculoskeletal disease 2020, Vol.12, p.1759720X20937132-1759720X20937132
Hauptverfasser: Thomas, Konstantinos, Lazarini, Argiro, Kaltsonoudis, Evripidis, Drosos, Alexandros, Papalopoulos, Ioannis, Sidiropoulos, Prodromos, Tsatsani, Panagiota, Gazi, Sousana, Pantazi, Lina, Boki, Kyriaki A., Katsimbri, Pelagia, Boumpas, Dimitrios, Fragkiadaki, Kalliopi, Tektonidou, Maria, Sfikakis, Petros P., Karagianni, Konstantina, Sakkas, Lazaros I., Grika, Eleftheria P., Vlachoyiannopoulos, Panagiotis G., Evangelatos, Gerasimos, Iliopoulos, Alexios, Dimitroulas, Theodoros, Garyfallos, Alexandros, Melissaropoulos, Konstantinos, Georgiou, Panagiotis, Areti, Maria, Georganas, Constantinos, Vounotrypidis, Periklis, Kitas, George D., Vassilopoulos, Dimitrios
Format: Artikel
Sprache:eng
Schlagworte:
Age groups
Body mass index
Comorbidity
Drug therapy
Gender differences
Immunotherapy
Original Research
Pathology
Rheumatoid arthritis
Risk factors
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Zusammenfassung:Background: Data regarding the real-life predictors of low disease activity (LDA) in rheumatoid arthritis (RA) patients are limited. Our aim was to evaluate the rate and predictors of LDA and treatment patterns in RA. Methods: This was a multicenter, prospective, RA cohort study where patients were evaluated in two different time points approximately 12 months apart. Statistical analysis was performed in order to identify predictors of LDA while patterns of disease-modifying anti-rheumatic drug [DMARDs; conventional synthetic (csDMARD) or biologic (bDMARD)] and glucocorticoid (GC) use were also recorded. Results: The total number of patients included was 1317 (79% females, mean age: 62.9 years, mean disease duration: 10.3 years). After 1 year, 57% had achieved LDA (DAS28ESR
ISSN:1759-720X
1759-7218
DOI:10.1177/1759720X20937132