Elevated leukotriene B4 and 8-isoprostane in exhaled breath condensate from preterm-born infants

Elevated leukotriene B4 and 8-isoprostane in exhaled breath condensate from preterm-born infants

Inflammation and oxidative stress play a key role in the development of bronchopulmonary dysplasia (BPD), possibly contributing to persistent respiratory morbidity after preterm birth. We aimed to assess if inflammatory markers were elevated in exhaled breath condensate (EBC) of infants born very pr...

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Veröffentlicht in:BMC pediatrics 2023-08, Vol.23 (1), p.386-386, Article 386
Hauptverfasser: Urs, Rhea, Ni Chin, Rubi, Hemy, Naomi, Wilson, Andrew C, Pillow, J Jane, Hall, Graham L, Simpson, Shannon J
Format: Artikel
Sprache:eng
Schlagworte:
Airway management
Artificial respiration
Asthma
Biomarkers
Breath Tests
Bronchopulmonary dysplasia
Bronchopulmonary Dysplasia - diagnosis
Care and treatment
Diagnosis
Female
Health aspects
Hospitals
Humans
Infant
Infant, Newborn
Infant, Premature
Infants (Premature)
Infections
Inflammation
Leukotriene B4 - analysis
Lung diseases
Mann-Whitney U test
Neutrophils
Newborn babies
Oxidative stress
Patient outcomes
Premature babies
Premature Birth
Preterm
Questionnaires
Respiratory diseases
Ventilators
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Zusammenfassung:Inflammation and oxidative stress play a key role in the development of bronchopulmonary dysplasia (BPD), possibly contributing to persistent respiratory morbidity after preterm birth. We aimed to assess if inflammatory markers were elevated in exhaled breath condensate (EBC) of infants born very prematurely (
ISSN:1471-2431
1471-2431
DOI:10.1186/s12887-023-04210-y