Perceptions of generic medicines and medication adherence after percutaneous coronary intervention: a prospective multicentre cohort study

ObjectiveTo determine patient perceptions of generic medicines 2 and 6 months after percutaneous coronary intervention (PCI), and to determine whether these perceptions moderate medication adherence.DesignProspective multicentre cohort study with repeated measures of perceptions of generic medicines...

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Veröffentlicht in:BMJ open 2022-09, Vol.12 (9), p.e061689
Hauptverfasser: Pettersen, Trond Røed, Schjøtt, Jan, Allore, Heather G, Bendz, Bjørn, Borregaard, Britt, Fridlund, Bengt, Larsen, Alf Inge, Nordrehaug, Jan Erik, Rotevatn, Svein, Wentzel-Larsen, Tore, Norekvål, Tone Merete
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Sprache:eng
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Zusammenfassung:ObjectiveTo determine patient perceptions of generic medicines 2 and 6 months after percutaneous coronary intervention (PCI), and to determine whether these perceptions moderate medication adherence.DesignProspective multicentre cohort study with repeated measures of perceptions of generic medicines and medication adherence.SettingThe CONCARDPCI study conducted at seven large referral PCI centres in Norway and Denmark between June 2017 and May 2020.ParticipantsA total of 3417 adults (78% men), using both generic and brand name medicines, with a mean age of 66 years (SD 11) who underwent PCI were followed up 2 and 6 months after discharge from hospital.Main outcome measuresPerceptions of generic medicines were the main outcome. The secondary outcome was medication adherence.ResultsPerceptions of generic medicines were significantly more negative at 2 than at 6 months (1.10, 95% CI 0.41 to 1.79, p=0.002). Female sex (−4.21, 95% CI −6.75 to −1.71, p=0.001), older age (−0.12, 95% CI −0.23 to −0.02, p=0.020), lower education level (overall p
ISSN:2044-6055
2044-6055
DOI:10.1136/bmjopen-2022-061689