Extensive Dermatophytosis Caused by Terbinafine-Resistant Trichophyton indotineae, France

Extensive Dermatophytosis Caused by Terbinafine-Resistant Trichophyton indotineae, France

Extensive dermatophytosis caused by terbinafine-resistant Trichophyton indotineae harboring Phe397Leu and Leu393Ser substitutions in the squalene epoxidase enzyme was diagnosed in France. Analysis of internal transcribed spacer sequences revealed the wide spread of this species in Asia and Europe. D...

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Veröffentlicht in:Emerging infectious diseases 2022-01, Vol.28 (1), p.229-233
Hauptverfasser: Jabet, Arnaud, Brun, Sophie, Normand, Anne-Cecile, Imbert, Sebastien, Akhoundi, Mohammad, Dannaoui, Eric, Audiffred, Laeticia, Chasset, Francois, Izri, Arezki, Laroche, Liliane, Piarroux, Renaud, Bachmeyer, Claude, Hennequin, Christophe, Sabater, Alicia Moreno
Format: Artikel
Sprache:eng
Schlagworte:
Antifungal agents
Antifungal Agents - pharmacology
Antifungal Agents - therapeutic use
Antimicrobial agents
antimicrobial resistance
Arthrodermataceae
Ascomycota
Causes of
Dermatomycoses
dermatophytosis
Dispatch
Distribution
Drug resistance in microorganisms
Drug Resistance, Fungal
Drug therapy
Extensive Dermatophytosis Caused by Terbinafine-Resistant
France
France - epidemiology
Fungal infections
Fungi
Genetic aspects
Humans
Identification and classification
Life Sciences
Microbial Sensitivity Tests
Mutation
Original Research
Pathogens
Patients
ringworm
skin conditions
Taxonomy
Terbinafine
Tinea - diagnosis
Tinea - drug therapy
Trichophyton - genetics
Trichophyton indotineae
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Zusammenfassung:Extensive dermatophytosis caused by terbinafine-resistant Trichophyton indotineae harboring Phe397Leu and Leu393Ser substitutions in the squalene epoxidase enzyme was diagnosed in France. Analysis of internal transcribed spacer sequences revealed the wide spread of this species in Asia and Europe. Detection of T. indotineae in animals suggests their possible role as reservoirs.
ISSN:1080-6040
1080-6059
1080-6059
DOI:10.3201/eid2801.210883