Effect of oral sucrose on pain during DPT immunization in older infants

[...]if there is proven and definite advantage of sucrose use during immunization on pain perception of infants its contradiction with exclusive breastfeeding may be sorted out. [...]this experimental study of infants aged 6 months or more attending the MCH clinic of Howrah General Hospital, West Bengal, India for DPT vaccination in the months of December 2009 and January 2010 was undertaken. Ethical and administrative clearance was sought and obtained from the appropriate authority. Since the institutional ethical committee permitted to undertake the study amongst infants aged 6-11 months all such infants attending the clinic during the study period and whose guardians agreed to participate in the study by giving written informed consent were included in the study. [4] Lindh et al., [5] showed less crying and less change in modified behavioral pain scores, as well as lower parent and nurse visual analog scale scores, for 3-month-old children who received local application of anesthetic cream and oral glucose, compared with placebo cream plus sterile water, before DPT immunization.