Association between plasma-free haemoglobin and postoperative acute kidney injury in paediatric cardiac surgery: a prospective observational study

Association between plasma-free haemoglobin and postoperative acute kidney injury in paediatric cardiac surgery: a prospective observational study

Acute kidney injury (AKI) is a common complication among patients requiring cardiopulmonary bypass (CPB) during paediatric cardiac surgery. Plasma-free haemoglobin (PFH) produced by haemolysis during CPB contributes to AKI. This study aimed to determine the association between PFH and postoperative...

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Veröffentlicht in:BJA open 2024-12, Vol.12, p.100348, Article 100348
Hauptverfasser: Sakura, Takanobu, Kanazawa, Tomoyuki, Shimizu, Tatsuhiko, Shimizu, Kazuyoshi, Iwasaki, Tatsuo, Morimatsu, Hiroshi
Format: Artikel
Sprache:eng
Schlagworte:
acute kidney injury
cardiopulmonary bypass
observational study
Original
paediatric cardiac surgery
plasma-free haemoglobin
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Zusammenfassung:Acute kidney injury (AKI) is a common complication among patients requiring cardiopulmonary bypass (CPB) during paediatric cardiac surgery. Plasma-free haemoglobin (PFH) produced by haemolysis during CPB contributes to AKI. This study aimed to determine the association between PFH and postoperative AKI during paediatric cardiac surgery requiring CPB. This prospective, single-centre, observational study included children aged
ISSN:2772-6096
2772-6096
DOI:10.1016/j.bjao.2024.100348