Development of Small-Molecule MERS-CoV Inhibitors

Middle East respiratory syndrome coronavirus (MERS-CoV) with potential to cause global pandemics remains a threat to the public health, security, and economy. In this review, we focus on advances in the research and development of small-molecule MERS-CoV inhibitors targeting different stages of the...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Viruses 2018-12, Vol.10 (12), p.721
Hauptverfasser:	Liang, Ruiying, Wang, Lili, Zhang, Naru, Deng, Xiaoqian, Su, Meng, Su, Yudan, Hu, Lanfang, He, Chen, Ying, Tianlei, Jiang, Shibo, Yu, Fei
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antiviral Agents - pharmacology Coronavirus Infections - drug therapy Coronaviruses Drug Discovery Enzymes Genomes Humans Infections Life cycles mechanism of action MERS-CoV Mice Middle East respiratory syndrome Middle East Respiratory Syndrome Coronavirus - drug effects Middle East Respiratory Syndrome Coronavirus - physiology Pandemics Pandemics - prevention & control Peptides Proteins Public health Respiratory diseases Review Small Molecule Libraries - pharmacology small-molecule inhibitor Virus Replication - drug effects Viruses
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Middle East respiratory syndrome coronavirus (MERS-CoV) with potential to cause global pandemics remains a threat to the public health, security, and economy. In this review, we focus on advances in the research and development of small-molecule MERS-CoV inhibitors targeting different stages of the MERS-CoV life cycle, aiming to prevent or treat MERS-CoV infection.
ISSN:	1999-4915 1999-4915
DOI:	10.3390/v10120721