Hydroa vacciniforme-like lymphoma with systemic symptoms: Two case reports

Two Chinese children presented with relapsing papules, vesicles, ulcers on the face and limbs with systemic symptoms being caused by mosquito bite. Lesion biopsy revealed atypical lymphocyte in the dermis and subcutis. Immunohistochemistry identified cells as positive for CD3, CD45RO, TIA-1 and EBER...

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Veröffentlicht in:Indian journal of dermatology 2019-11, Vol.64 (6), p.493-496
Hauptverfasser: Wang, Litao, Su, Yuwen, Zhang, Jianzhong, Wen, Haiquan, Zhang, Guiying
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Sprache:eng
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Zusammenfassung:Two Chinese children presented with relapsing papules, vesicles, ulcers on the face and limbs with systemic symptoms being caused by mosquito bite. Lesion biopsy revealed atypical lymphocyte in the dermis and subcutis. Immunohistochemistry identified cells as positive for CD3, CD45RO, TIA-1 and EBER. Taken together, both the patients were diagnosed with hydroa vacciniforme-like lymphoma. Two patients showed significant improvement in clinical symptoms after being treated with acyclovir, low dose predisone and IFN-α.
ISSN:0019-5154
1998-3611
DOI:10.4103/ijd.IJD_178_18