Intrauterine Transmission of SARS-CoV-2

We documented fetal death associated with intrauterine transmission of severe acute respiratory syndrome coronavirus 2. We found chronic histiocytic intervillositis, maternal and fetal vascular malperfusion, microglial hyperplasia, and lymphocytic infiltrate in muscle in the placenta and fetal tissu...

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Veröffentlicht in:	Emerging infectious diseases 2021-02, Vol.27 (2), p.638-641
Hauptverfasser:	Stonoga, Emanuele T S, de Almeida Lanzoni, Laura, Rebutini, Patricia Zadorosnei, Permegiani de Oliveira, André Luiz, Chiste, Jullie Anne, Fugaça, Cyllian Arias, Prá, Daniele M M, Percicote, Ana Paula, Rossoni, Andrea, Nogueira, Meri Bordignon, de Noronha, Lucia, Raboni, Sonia Mara
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Amniotic fluid autopsy Congenital diseases congenital transmission Coronaviruses COVID-19 COVID-19 - transmission COVID-19 - virology Disease transmission Diseases Expedited Female Fetal Death - etiology Fetus - virology Fetuses Health aspects Humans Hypertension Infants (Newborn) Infections Infectious Disease Transmission, Vertical Intrauterine Transmission of SARS-CoV-2 Maternal-fetal exchange Medical diagnosis Obstetrics Pathology Patients placenta Placenta - virology Pregnancy Pregnancy Complications, Infectious - virology Pregnant women Research Letter SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 stillbirth Thrombosis Ultrasonic imaging Umbilical cord Womens health
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Beschreibung
Zusammenfassung:	We documented fetal death associated with intrauterine transmission of severe acute respiratory syndrome coronavirus 2. We found chronic histiocytic intervillositis, maternal and fetal vascular malperfusion, microglial hyperplasia, and lymphocytic infiltrate in muscle in the placenta and fetal tissue. Placenta and umbilical cord blood tested positive for the virus by PCR, confirming transplacental transmission.
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid2702.203824