Influence of bone cement distribution on outcomes following percutaneous vertebroplasty: a retrospective matched-cohort study

Objective To evaluate the influence of insufficient bone cement distribution on outcomes following percutaneous vertebroplasty (PVP). Methods This retrospective matched-cohort study included patients 50–90 years of age who had undergone PVP for single level vertebral compression fractures (VCFs) fro...

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Veröffentlicht in:Journal of international medical research 2021-07, Vol.49 (7), p.3000605211022287-3000605211022287
Hauptverfasser: Mo, Ling, Wu, Zixian, Liang, De, Y, Linqiang, Cai, Zhuoyan, Huang, Jinjing, Lin, Shunxin, Cui, Jianchao, Zhang, Shuncong, Yang, Zhidong, Yao, Zhensong, Jiang, Xiaobing
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Sprache:eng
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Zusammenfassung:Objective To evaluate the influence of insufficient bone cement distribution on outcomes following percutaneous vertebroplasty (PVP). Methods This retrospective matched-cohort study included patients 50–90 years of age who had undergone PVP for single level vertebral compression fractures (VCFs) from February 2015 to December 2018. Insufficient (Group A)/sufficient (Group B) distribution of bone cement in the fracture area was assessed from pre- and post-operative computed tomography (CT) images. Assessments were before, 3-days post-procedure, and at the last follow-up visit (≥12 months). Result Of the 270 eligible patients, there were 54 matched pairs. On post-operative day 3 and at the last follow-up visit, significantly greater visual analogue scale (VAS) pain scores and Oswestry Disability Index (ODI) scores were obtained in Group B over Group A, while kyphotic angles (KAs) and vertebral height (VH) loss were significantly larger in Group A compared with Group B. Incidence of asymptomatic cement leakage and re-collapse of cemented vertebrae were also greater in Group A compared with Group B. Conclusions Insufficient cement distribution may relate to less pain relief and result in progressive vertebral collapse and kyphotic deformity post-PVP.
ISSN:0300-0605
1473-2300
DOI:10.1177/03000605211022287