Evaluation of Urinary Neutrophil Gelatinase Associated Lipocalin and Kidney Injury Molecule-1 as Diagnostic Markers for Early Nephropathy in Patients with Type 2 Diabetes Mellitus

The purpose of this study was evaluating the early diagnostic value of two specific tubular markers neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule-1 (KIM-1) in diabetes nephropathy. Cross-sectional study was carried in three groups of patients from 10/2017 to 10/2018 in...

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Veröffentlicht in:	Diabetes, metabolic syndrome and obesity metabolic syndrome and obesity, 2020-01, Vol.13, p.2199-2207
Hauptverfasser:	Quang, Thuan Huynh, Nguyet, Minh Pham, Thao, Diep Pham, Thi, Minh Hoang, Phuong Thi Dam, Lan, Thi, Hang Ho, Van, Anh Phan, Luong, Thang Can, Tuyet, Mai Ngo Thi, Duy, Quy Dang, Nhu, Binh Do, Duc, Thuan Nghiem
Format:	Artikel
Sprache:	eng
Schlagworte:	Albumin albumin urine Care and treatment diabetic kidney disease Diabetic nephropathies Diabetics Diagnosis Original Research Type 2 diabetes urine albumin creatinin ratio
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Beschreibung
Zusammenfassung:	The purpose of this study was evaluating the early diagnostic value of two specific tubular markers neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule-1 (KIM-1) in diabetes nephropathy. Cross-sectional study was carried in three groups of patients from 10/2017 to 10/2018 in Military Hospital 103. Group I included 30 healthy peoples with estimated glomerular filtration rate (eGFR) >60 mL/min/1.73 m and urine albumin creatinine ratio (uACR) 30 mg/g, eGFR >60 mL/min/1.73 m . Urine KIM-1 and NGAL increased progressively from control group (57.29 ± 25.91 pg/mL; 25.71 ± 13.69 ng/mL) to the group of diabetic patients with uACR
ISSN:	1178-7007 1178-7007
DOI:	10.2147/DMSO.S258678