P39 Acute Responses of Pulse Wave Reflection after Aerobic Exercise with Different Volumes

Background Although Aerobic Exercise (AE) has been recognized for lowering Blood Pressure (BP), little is known about the alterations in aortic BP after exercise (1,2). PURPOSE: To investigate the acute pulse wave reflection responses induced by AE with different volumes in normotensive and hypertensive men. Methods We included 12 normotensives [aged: 38.3 ± 10.1 years, body mass index (BMI): 25.9 ±3.6 kg/m 2 , maximal oxygen uptake (VO2max): 31.4 ± 6.9 mL·kg −1 ·min −1 , systolic/diastolic BP (SBP/DBP): 121 ± 6/74 ± 4 mmHg] and 7 hypertensive men [aged: 39.1 ± 6.0 years, BMI: 29.4 ± 3.1 kg/m 2 , VO2max: 26.1 ± 1.8 mL·kg −1 ·min −1 , SBP/DBP: 140 ± 8/88 ± 7 mmHg]. The participants were submitted to a maximal cardiopulmonary exercise test, a non-exercise control session (CTL), and two bouts of continuous cycling at 50% VO2 reserve (150 vs. 300 kcal) in a randomized, counter-balanced order. Aortic systolic pressure, aortic pulse pressure, augmentation pressure, and augmentation index (AIx) were determined 10 min before and 70 min after the CTL and the two exercise bouts in a supine position by applanation tonometry (SphygmoCor v7). Results Central pressures and AIx were different between normotensive and hypertensive men after the two AE bouts as shown in table 1 . Conclusion Although both AE were able to reduce pulse wave reflection in hypertensive men, only the major volume has attenuated the increase in central aortic BP observed in the control session. Table 1 Mean ± SD values for the pulse wave reflection indicators at baseline and post- CTL and AE bouts with 150 and 300 kcal. Normotensive Hypertensive Variables Conditions Bascline Recovery Bascline Recovery Aortic Systolic Pressure (mmHg) CTL 150 kcal 300 kcal 99.83 ± 4.46 98.17 ± 6.21 100.25 ± 5.34 104.75 ±7.81† 99.08 ± 7.99 100.00 ± 6.9S 113.71 ± 14.52 114.71 ± 11.14 114.43 ± 15.14 124.86 ± 18.90† 124.43 ± 18.11* 119.57 ± 13 37 Aortic Pilse Pressure (mmHg) CTL 150 kcal 300 kcal 29.67 ± 3.72 28.00 ± 5.54 30.08 ± 3.31 28.67 ± 4.25 27.83 ± 3.56 27.75 ± 4.04 30.57 ± 7.48 31.29 ± 3 90 31.14 ± 7.75 35.29 ± 9.30 33.71 ± 5.99 32.29 ± 4.64 Aortic Augmentation Pressure (mmHg) CTL 150 kcal 300 kcal 4.83 ± 4.42 3.67 ± 5.08 3.08 ± 4.33 3.75 ± 3.51 1.58 ± 3.60 1.83 ± 3.83 3.43 ± 8.22 4.57 ± 3.10 4.00 ± 6.13 7.86 ± 5.52† 6.86 ± 5.52 5.43 ± 3.59 Augmentation Index (%) CTL 150 kcal 300 kcal 13 33 ± 10.22 10.75 ± 16.76 9.50 ± 13.54 11.83 ± 12.34 5.50 ±12.91 5.75 ± 12.48 10.43 ± 12.52 14.29 ± 8.46 10.14 ± 13.69 20.43 ±