MEDULLARY CONGESTION IN OVARY OF TOPICALLY APPLIED PARAPHENYLENE DIAMINE EFFECTED RAT

According to International Agency for Research on Cancer (IARC) there is an evidence that use of hair dye may cause carcinogen exposure leading to higher incidence of bladder cancer, non-Hodgkin's lymphoma, multiple myeloma, and hematopoietic cancers3. Exposure to PPD occurs through skin contact, accidental ingestion or inhalation of particles from hair dye formulation during dyeing. Solution of PPD was prepared in distilled water daily and 0.1ml of this solution was applied on the exposed dorsal surface of experimental animals of group B, C and D. Control group was applied with 0.1ml of distilled water alone. Toxicity effects of hair dye application on liver function in experimental animals.