Temporal Lobe Necrosis in Head and Neck Cancer Patients after Proton Therapy to the Skull Base

Temporal Lobe Necrosis in Head and Neck Cancer Patients after Proton Therapy to the Skull Base

To demonstrate temporal lobe necrosis (TLN) rate and clinical/dose-volume factors associated with TLN in radiation-naïve patients with head and neck cancer treated with proton therapy where the field of radiation involved the skull base. Medical records and dosimetric data for radiation-naïve patien...

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Veröffentlicht in:International journal of particle therapy 2020, Vol.6 (4), p.17-28
Hauptverfasser: Kitpanit, Sarin, Lee, Anna, Pitter, Ken L, Fan, Dan, Chow, James C H, Neal, Brian, Han, Zhiqiang, Fox, Pamela, Sine, Kevin, Mah, Dennis, Dunn, Lara A, Sherman, Eric J, Michel, Loren, Ganly, Ian, Wong, Richard J, Boyle, Jay O, Cohen, Marc A, Singh, Bhuvanesh, Brennan, Cameron W, Gavrilovic, Igor T, Hatzoglou, Vaios, O'Malley, Bernard, Zakeri, Kaveh, Yu, Yao, Chen, Linda, Gelblum, Daphna Y, Kang, Jung Julie, McBride, Sean M, Tsai, Chiaojung J, Riaz, Nadeem, Lee, Nancy Y
Format: Artikel
Sprache:eng
Schlagworte:
head and neck cancer
Original
proton therapy
temporal lobe necrosis
toxicity
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Zusammenfassung:To demonstrate temporal lobe necrosis (TLN) rate and clinical/dose-volume factors associated with TLN in radiation-naïve patients with head and neck cancer treated with proton therapy where the field of radiation involved the skull base. Medical records and dosimetric data for radiation-naïve patients with head and neck cancer receiving proton therapy to the skull base were retrospectively reviewed. Patients with
ISSN:2331-5180
2331-5180
DOI:10.14338/IJPT-20-00014.1